ea0073pep11.3 | Presented ePosters 11: Adrenal and Cardiovascular Endocrinology | ECE2021
Fei Laura
, Cantini Giulia
, Nocentini Alessio
, Canu Letizia
, Nardini Patrizia
, De Filpo Giuseppina
, Ercolino Tonino
, Nesi Gabriella
, Maggi Mario
, Bani Daniele
, Mannelli Massimo
, Supuran Claudiu T
, Luconi Michaela
The adipose tissue (AT) is an important endocrine organ. Upon energy imbalance, the adipose cells become dysfunctional, supporting the development of metabolic pathologies and tumours. The adipose cell is among the main actor of the tumor microenvironment, and is able to establish a crosstalk with the cancer cell resulting in a reciprocal reprogramming. Adrenocortical carcinoma (ACC) is a rare endocrine malignancy affecting the adrenal cortex. In the most aggressive forms, can...